The Science of Cellular Rejuvenation
Understanding how we reverse biological aging at the cellular level
For decades, scientists have searched for ways to slow or reverse aging. At Celljevity, we've developed Prometheus technology—a breakthrough approach that rejuvenates your own cells without altering your DNA.
From Lab Bench to Your Body
The Prometheus Process Simplified
20 Billion Rejuvenated Cells from a Biopsy Smaller Than a Dime
The Harvest
A 6mm × 6mm skin sample is collected from behind your ear—an area rich in dermal fibroblasts that respond exceptionally well to reprogramming. This tissue maintains high proliferative capacity even in older adults.
The Transformation
Your cells enter our GMP-certified laboratory where proprietary small-molecule compounds trigger controlled epigenetic reprogramming. Unlike Yamanaka factors, our protocol stops at the 'newborn cell' stage.
- Single-cell RNA sequencing
- Karyotype stability confirmed
- 95%+ viability check
Cellular Memory
Dr. Sun's innovation: safely reprogramming cells by stopping short of full pluripotency. This maintains mesenchymal stem cell-like properties without losing differentiation control or risking tumor formation.
Strategic Delivery
Cells migrate to inflammation sites via receptor-mediated homing. Prometheus Cells inherently 'sense' injury signals—damaged tissue releases cytokines that act like cellular GPS coordinates.
Safety Profile vs. Alternatives
| Therapy | Cell Source | Genetic Modification | Rejection Risk | Safety Record |
|---|---|---|---|---|
| Prometheus | Your own fibroblasts | None (epigenetic only) | 0% | 1,000 patients, 0 serious events |
| Allogeneic MSCs | Donor cells | None | 10-20% | Variable donor quality |
| CAR-T Therapy | Modified T-cells | CRISPR editing | Low but complex | FDA black box warning |
| iPSC Derivatives | Reprogrammed cells | Yamanaka factors | Variable | Teratoma risk remains |
Why Do We Age?
Every cell in your body contains biological clocks called telomeres—protective caps on your chromosomes that shorten with age. As telomeres shrink, cells lose their ability to function properly, leading to the signs and symptoms we associate with aging.
Additionally, your cells accumulate 'epigenetic marks'—chemical tags that tell genes when to turn on or off. Over time, these marks accumulate errors, like typos in an instruction manual, causing cells to forget how to function youthfully.
Key Mechanisms of Aging:
- Telomeres shorten by ~1-2% per year naturally
- Epigenetic changes affect how genes are expressed
- Cellular damage accumulates over decades
- Traditional medicine treats symptoms, not causes
The Journey to Renewal
Your Rejuvenation Process
From collection to results in six precise steps, each designed to ensure the highest quality and safety standards for your cellular therapy.
Tissue Collection
A small 1cm² skin biopsy is collected from behind the ear under local anesthesia
Cell Isolation
Fibroblasts are isolated and expanded in our GMP-certified laboratories
Rejuvenation Protocol
Proprietary 15-day treatment reverses cellular aging markers to new-born stage
Quality Validation
Single-cell RNA sequencing confirms successful rejuvenation before release
Therapeutic Delivery
20 billion rejuvenated cells delivered via targeted injection or IV infusion
Results & Monitoring
Extended telomeres and rejuvenated cellular markers confirmed through comprehensive testing
Our complete rejuvenation process takes approximately 12 weeks from initial consultation to cell delivery
Learn MoreClinical Observations
Real Results from Real Patients
While our technology is still investigational and individual results vary, our clinical observations from over 1,000 patients show promising patterns:
Telomere Extension
Average increase in telomere length
Cognitive Function
Alzheimer's patients maintained or improved
Autoimmune Relief
Reported significant symptom improvement
Joint Health
Osteoarthritis patients showed improvement
Important Note: These are preliminary observational results. Formal clinical trials are ongoing to validate these findings. Results vary by individual.
Comparative Evidence
Why Epigenetic Reprogramming Outperforms
The longevity industry is crowded with promises. Here's how Prometheus Therapy compares using published scientific evidence, not marketing claims.
| Technology | Company Example | Approach | Key Risk | Clinical Stage |
|---|---|---|---|---|
Epigenetic Reprogramming | Celljevity | Small-molecule reset to 'newborn' state | Minimal (1,000 patients, 0 serious AEs) | 1,000+ patients treated |
Partial Yamanaka | Altos Labs, Retro Bio | In vivo gene therapy (OSKM) | Teratoma risk if overdone | Preclinical (animal studies) |
CRISPR Base Editing | Verve Therapeutics | Permanent DNA changes | Off-target edits; irreversible | Phase I trials |
Senolytics Only | Unity Biotechnology | Clear senescent cells | Doesn't regenerate tissue | Phase II |
Allogeneic MSCs | Mesoblast | Donor stem cells | 10-20% rejection; GVHD risk | Phase III |
Epigenetic vs. Genetic Editing
The Stanford Insight
"Unlike gene editing, epigenome editing is reversible, safer, and promising for complex diseases." — Dr. Mark Mercola
CRISPR
Permanent DNA Rewrite
Irreversible
Epigenetics
Gene Expression Reset
Fully Reversible
The Cancer Question
Standard Yamanaka reprogramming (OSKM) creates pluripotent stem cells that can form teratomas (tumors). Celljevity's innovation stops at the mesenchymal stem cell-like stage—retaining regenerative capacity without tumor risk.
Safety Record
7 Years
Patients
1,000+
Teratomas
Zero
Safety First
Your Safety is Our Priority
With over 1,000 patients treated since 2018, we maintain the highest safety standards because we're not just treating patients—we're pioneering a new field of medicine.
Explore Our Research
Dive deeper into our 100+ peer-reviewed publications, key research findings, and scientific breakthroughs in our blog.
Medical Disclaimer: Celljevity's Prometheus technology is currently investigational and not approved by the FDA. Treatment availability varies by jurisdiction. Individual results may vary. Please consult with your healthcare provider. The statements on this website have not been evaluated by the Food and Drug Administration. Our treatments are not intended to diagnose, treat, cure, or prevent any disease.